I'm not sure but I came across this by googling:
Desktop tools
Borland Genetics Kevin Borland's free toolkit for reconstructing GedMatch-compatible synthetic DNA kits for deceased ancestors using raw DNA files of living relatives.
and this:
Lazarus is one of the Tier 1 utilities offered by GedMatch. It allows you to recreate at least some of an ancestor's genome, based on living relatives who have tested. It takes two sets of kits--one set consists of descendants of the ancestor whose DNA you're trying to recreate (Group 1); the second set consists of non-descendant relatives of that individual (Group 2).
So it looks as though "synthetic" means that it isn't from an actual DNA sample.
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